HEALTH PRODUCTS ARTICLE
Turn Off Your Obesity Gene
By Dr. Al Sears
Have you resigned yourself to gaining weight because it
“runs in the family”?
Bad genetics doesn’t have to catch up with you. You can
change your genes simply by making a few adjustments to your diet.1
When you eat certain foods, nutrients release hormones
that switch your genes on and off. And the nutrients in low-glycemic foods turn
off genes that lead to weight gain and diseases that may follow.
We found this out when we studied the response to the
glycemic index (GI) in people who have metabolic syndrome.
The glycemic index measures how fast your food breaks down
to sugar in your bloodstream. Metabolic syndrome is a medical term for
overweight people whose cholesterol, triglycerides, and blood sugar levels are
high. It puts them at risk for diabetes, heart attack, and stroke.
In the study, one group ate foods with a low GI rating of
40-60. The other group ate foods with a high GI rating of about 80-100.
In just 12 weeks, the high GI diet increased the
activity of 62 genes that lead to disease. These genes activate your
stress response. It puts your body in a constant “fight or flight” mode. This
lowers your immunity and causes damage to your cells.
But the low GI diet decreased the activity of 71 disease-causing
genes, including hormone-sensitive lipase (HSL).2
High HSL is what causes fat to settle around your middle.3 But
when scientists studied animals bred to have little HSL, they found the animals
became resistant to obesity, whether it was hereditary or from diet.4
I suggest you eat a wide variety of low GI foods. Follow
the example handed down by our primal ancestors. Choose foods you could have
gotten either by hunting or gathering:
Eat fresh, low-glycemic foods. Look
for grass-fed beef. Fish. Beans. Plenty of above-ground and green, leafy
vegetables. Onions and garlic. Berries, nuts, and seeds. Fresh fruits.
Avoid high-glycemic foods. These
include white potatoes, most grains such as rice, corn, and wheat, cereals,
cereal bars, and low-fiber or sweetened foods.
Shun pre-packaged items and fast food. These
products contain high-glycemic ingredients and artificial chemicals. Avoid
sweetened foods. Diet foods. Foods like these turn on the genes responsible for
weight gain and disease.5
For more information on the glycemic index, click here.
Finally, if you have a family history of disease, you may
want to supplement with additional nutrients:
Pick up a multi-vitamin and mineral supplement that
contains high levels of B vitamins such as B12 and folate. These two vitamins
directly contribute to DNA health. I recommend at least 100 mcg per day of
vitamin B12 and 800 mcg of folate.
MSM is a great detoxifier known to keep your DNA healthy.
You can take 900 mg up to 3 times a day.
SAMe is a nutrient you won’t find in food, but you can buy
supplements at your local vitamin shop. This is one of the best-known for DNA
protection. Take 200-1,600 mg daily.
***
***
Sources
2 Kallio P, Kolehmainen M, Laaksonen DE, et al. “Dietary carbohydrate modification induces alterations in gene expression in abdominal subcutaneous adipose tissue in persons with the metabolic syndrome: the FUNGENUT Study.” Am J Clin Nutr 2007;85:1417–27.
3 Carlsson, E. et al. “The hormone-sensitive lipase C–60G promoter polymorphism is associated with increased waist circumference in normal-weight subjectsHormone-sensitive lipase and obesity.” International Journal of Obesity 2006, Sept;30: 1442-1448.
4 Sekiya M, Osuga JL, Okazaki H, et al. “Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.” J Biol Chem 2004;279:15084–90.
5 Salsberg SL, Ludwig DS. “Putting your genes on a diet: the molecular effects of carbohydrate.” Am J Clin Nutr. 2007 May;85(5):1169-70.
Health and Humor
Voltaire
(and your grandmother) recognized long ago
that humor and laughter are good for you. You've probably noticed
yourself that
you simply feel better after a good belly laugh. The problem, of
course, is
that your sense of humor generally abandons you right when you need it
the most
– on the tough days. But if you manage to bring your sense of humor to
your
daily conflicts on your job, your relationship with your spouse and
children,
and your health or financial problems, you'll go a long way toward
improving
the quality of your life; and you'll boost your physical health and
well-being.
– Paul E. McGhee, PhD
“Never go to a doctor whose office plants have died. ”
- Erma Bombeck
Note: The good
folks at the FTC require me to disclose that I am an affiliate of the
companies that manufacture and market the health products you will find
on this website, and that these companies will compensate me if you buy
any of these products.
– Dave Tishendorf